Application Benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside (BADGP), an O-GlcNAc (OGT) transferase inhibitor, is used to study the physiological effects of O-glycosylation modulation. Biochem/physiol Actions Benzyl-N-acetyl-α-galactosaminide inhibits glycosyltransferase incorporation of glucosamine into O-glycans. Suppresses mucin biosynthesis1,2 and inhibits MUC1 expression in breast cancer cell line MDF-7.3 |