Erythromycin estolate

• 产品号: E8630
• CAS号: 3521-62-8
• 分子式: C49H93NO17S
• 分子量: 1000.32422

产品别名

• 标题: Erythromycin estolate
• IUPAC标准名: (3S,4R,5R,6S,7S,9S,12R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; (dodecyloxy)sulfonic acid
• IUPAC传统名: (3S,4R,5R,6S,7S,9S,12R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione N-dodecyl sulfate
• 别名: Erythromycin 2′-propionate dodecyl sulfate

产品登记号

• CAS号: 3521-62-8
• EC号: 222-532-4
• PubChem SID: 24894679
• MDL号: MFCD00084691

产品性质

• GHS警示词: Danger
• GHS危险声明: H302-H317-H334
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P261-P280-P342 + P311
• 危险公开号: 22-42/43
• 安全公开号: 22-36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Erythoromycin estolate is used to study hepatic cytochrome P-450 induction and inactivation via cytochrome-metabolite complex formation1 and Giardia intestinalis inefections2. It is used to study antibiotic cytotoxicity in cultured human liver cell lines3.
Biochem/physiol Actions
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site) by binding to the 50s subunit of the bacterial 70s rRNA complex.
Erythromycin inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).