Tropisetron

• 产品号: T104
• CAS号: 105826-92-4
• 分子式: C17H21ClN2O2
• 分子量: 320.81384
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Tropisetron monohydrochloride
• IUPAC标准名: 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
• IUPAC传统名: 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
• 别名: ICS-205,930; 3-Tropanylindole-3-carboxylate monohydrochloride; endo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ol Indol-3-yl-carboxylate 盐酸盐; Navoban

产品登记号

• CAS号: 105826-92-4
• PubChem SID: 24278133
• MDL号: MFCD00210221

产品性质

• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242)rat ... Chrna7(25302), Drd2(24318), Htr1a(24473), Htr3a(79246)
• 外观: solid
• 溶解度: H2O: >10 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.