(Z)-4-Hydroxytamoxifen

• 产品号: H7904
• CAS号: 68047-06-3
• 分子式: C26H29NO2
• 分子量: 387.51396
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: (Z)-4-Hydroxytamoxifen
• IUPAC标准名: 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
• IUPAC传统名: 4-hydroxytamoxifen
• 别名: (Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol; trans-4-Hydroxytamoxifen; (Z)-4-OHT

产品登记号

• PubChem SID: 24895814
• MDL号: MFCD00278780
• CAS号: 68047-06-3

产品性质

• 纯度: ≥98% (HPLC)
• 产品质量级别: PREMIUM
• 相关基因信息: human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)rat ... Ar(24208), Esr1(24890), Esr2(25149)
• 外观: powder
• 溶解度: methanol: soluble10 mg/mL
• 溶解度: ethanol: soluble20 mg/mL (with heating)
• GHS警示词: Warning
• GHS危险声明: H302-H312-H332-H361
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P280
• 危险公开号: 63-20/21/22
• RTECS编号: SL1210000
• 安全公开号: 22-23-36
• 保存条件: desiccated
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

General description
4-Hydroxytamoxifen is the active metabolite of tamoxifen which binds estrogen receptors (ER) and estrogen-related receptors (ERR) with estrogenic and anti-estrogenic effects. It is a selective estrogen receptor modulator (SERM).
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H7904.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.