6-(马来酰亚胺基)己酸琥珀酰亚胺酯

• 产品号: M9794
• CAS号: 55750-63-5
• 分子式: C14H16N2O6
• 分子量: 308.28664
• 纯 度: ≥98%

产品别名

• 标题: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
• IUPAC标准名: 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate
• IUPAC传统名: 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxopyrrol-1-yl)hexanoate
• 别名: EMCS; N-(ε-马来酰亚胺己酰氧)琥珀酰亚胺; 6-马来酰亚氨基己酸 N-琥珀酰亚胺酯; N-琥珀酰亚胺 6-马来酰亚胺己酸酯

产品登记号

• MDL号: MFCD00043043
• CAS号: 55750-63-5
• Beilstein号: 1499815

产品性质

• 纯度: ≥98%
• 外观: powder
• 熔点: 70-73 °C(lit.)
• 溶解度: chloroform: soluble100 mg/mL
• 溶解度: DMF: soluble (lit.)
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335-H351
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P261-P281-P305 + P351 + P338
• 危险公开号: 36/37/38-40
• 安全公开号: 26-36/37
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.