L-701,324

• 产品号: L0258
• CAS号: 142326-59-8
• 分子式: C21H14ClNO3
• 分子量: 363.79376
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: L-701,324
• IUPAC标准名: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1,2-dihydroquinolin-2-one
• IUPAC传统名: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one
• 别名: 7-Chloro-4-hydroxy-3-(3-phenoxy)phenylquinolin-2[1H]-one

产品登记号

• MDL号: MFCD00910917
• PubChem SID: 24278508
• CAS号: 142326-59-8

产品性质

• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... GRIN1(2902)rat ... Grin1(24408), Grin2a(24409)
• 外观: solid
• 溶解度: DMSO: soluble36.4 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Legal Information
Manufactured and sold under license from Merck, Sharp and Dohme, Ltd. U.S. Patent No. 5,348,962.
Biochem/physiol Actions
L-701,324 is a high affinity, selective antagonist at the glycine site of the NMDA glutamate receptor. L-701,324 is a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents.