Capreomycin sulfate from Streptomyces capreolus

• 产品号: C4142
• CAS号: 1405-37-4
• 分子式: C24H44N14O12S
• 分子量: 752.75776

产品别名

• 标题: Capreomycin sulfate from Streptomyces capreolus
• IUPAC标准名: (2S)-2,5-diamino-N-{[(2S,5R,8Z,11S,15R)-15-amino-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-11-(2-imino-1,3-diazinan-4-yl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-5-yl]methyl}pentanamide; sulfuric acid
• IUPAC传统名: (2S)-2,5-diamino-N-{[(2S,5R,8Z,11S,15R)-15-amino-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-11-(2-imino-1,3-diazinan-4-yl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-5-yl]methyl}pentanamide; sulfuric acid

产品登记号

• CAS号: 1405-37-4
• MDL号: MFCD00079032
• PubChem SID: 24892668
• EC号: 215-776-8

产品性质

• GHS警示词: Danger
• GHS危险声明: H302-H312-H332-H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P280-P308 + P313
• 危险公开号: 61-20/21/22
• RTECS编号: EX8930000
• 安全公开号: 53-22-36/37/39-45
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Capreomycin is a cyclic peptide antibiotic that is often grouped with aminoglycosides. It is a second line antibiotic and is used to study multidrug-resistant tuberculosis 1,2.
Capreomycin sulfate is used to study bacterial ribosomal subunit interactions and translocation processes during protein synthesis.
Biochem/physiol Actions
Capreomycin sulfate binds across the ribosomal interface involving 23S rRNA helix 69 (H69) and 16S rRNA helix 44 (h44) 3.