Coumermycin A1

• 产品号: C9270
• CAS号: 4434-05-3
• 分子式: C55H59N5O20
• 分子量: 1110.07846

产品别名

• 标题: Coumermycin A1
• IUPAC标准名: (3R,4S,5R,6R)-5-hydroxy-6-[(4-hydroxy-3-{5-[(4-hydroxy-7-{[(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-(5-methyl-1H-pyrrole-2-carbonyloxy)oxan-2-yl]oxy}-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl]-4-methyl-1H-pyrrole-3-amido}-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyloxan-4-yl 5-methyl-1H-pyrrole-2-carboxylate
• IUPAC传统名: (3R,4S,5R,6R)-5-hydroxy-6-[(4-hydroxy-3-{5-[(4-hydroxy-7-{[(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-(5-methyl-1H-pyrrole-2-carbonyloxy)oxan-2-yl]oxy}-8-methyl-2-oxochromen-3-yl)carbamoyl]-4-methyl-1H-pyrrole-3-amido}-8-methyl-2-oxochromen-7-yl)oxy]-3-methoxy-2,2-dimethyloxan-4-yl 5-methyl-1H-pyrrole-2-carboxylate

产品登记号

• MDL号: MFCD00057312
• CAS号: 4434-05-3
• Beilstein号: 470805

产品性质

• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• RTECS编号: UX9375000
• 安全公开号: 36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria1.
Application
Coumermycin A1 is an aminocoumarin antibiotic used to study processes such as DNA replication, transcription, and recombination that involve DNA topoisomerase II activity. It has been used to treat Staphylococcus aureus endocarditis in the rat model1 and to study the effect of coumermycin A1 on the expression of 67 fusions in Salmonella typhimurium. 2.
Coumermycin A1 is used to study processes such as DNA replication, transcription, and recombination that involve DNA topoisomerase II activity.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C9270.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.