Retinoic acid

• 产品号: R2625
• CAS号: 302-79-4
• 分子式: C20H28O2
• 分子量: 300.43512
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Retinoic acid
• IUPAC标准名: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• IUPAC传统名: tretinoin
• 别名: tretinoin; ATRA; all-trans-Retinoic acid; Vitamin A acid

产品登记号

• EC号: 206-129-0
• PubChem SID: 24278674
• MDL号: MFCD00001551
• CAS号: 302-79-4
• Beilstein号: 2057223

产品性质

• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)mouse ... Rara(19401), Rarb(218772), Rarg(19411), Rxrb(20182)
• 外观: yellow powder
• 熔点: 180-181 °C(lit.)
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• RTECS编号: VH6475000
• 安全公开号: 61
• 保存温度: -20°C
• 德国WGK号: 2

产品详细信息

详细说明 (简体中文)

Frequently Asked Questions
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包装
1, 5 g in ampule
50, 100, 500 mg in ampule
Sealed ampule
Biochem/physiol Actions
all-trans-Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R2625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.