Acetyl coenzyme A 钠盐

• 产品号: A2056
• CAS号: 102029-73-2
• 分子式: C23H37N7NaO17P3S
• 分子量: 831.552633
• 纯 度: ≥93% (HPLC)

产品别名

• 标题: Acetyl coenzyme A sodium salt
• IUPAC标准名: sodium (2R,3S,4R,5R)-2-[({[({3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl hydrogen phosphate
• IUPAC传统名: sodium (2R,3S,4R,5R)-2-{[({3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxy]methyl}-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-3-yl hydrogen phosphate
• 别名: Acetyl CoA; Acetyl-S- CoA

产品登记号

• CAS号: 102029-73-2
• PubChem SID: 24890621
• MDL号: MFCD00078858

产品性质

• 纯度: ≥93% (HPLC)
• 产品质量级别: PREMIUM
• 相关基因信息: human ... CHAT(1103), HAT1(8520), KAT2A(2648), KAT2B(8850), KAT5(10524)mouse ... HAT1(107435), KAT2A(14534), KAT2B(18519), KAT5(81601)rat ... HAT1(296501), KAT2A(303539), KAT2B(301164), KAT5(192218)
• 外观: powder
• 溶解度: H2O: soluble100 mg/mL
• 个人保护装置: Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Frequently Asked Questions
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Application
An essential cofactor in enzymatic acetyl transfer reactions.
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.
Other Notes
For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.
Preparation Note
Prepared enzymatically
Biochem/physiol Actions
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.