Guanosine 3′,5′-cyclic monophosphate sodium salt

• 产品号: G6129
• CAS号: 40732-48-7
• 分子式: C10H11N5NaO7P
• 分子量: 367.187171
• 纯 度: ≥99% (HPLC)

产品别名

• 标题: Guanosine 3′,5′-cyclic monophosphate sodium salt
• IUPAC标准名: sodium (4aR,6R,7R,7aS)-6-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC传统名: sodium 3',5'-cyclic gmp anion
• 别名: 3′,5′-cGMP-Na; Guanosine 3′,5′-cyclophosphate monosodium salt; cGMP; 3′,5′-Cyclic GMP monosodium salt; cyclic GMP

产品登记号

• CAS号: 40732-48-7
• PubChem SID: 24895245
• EC号: 255-056-0
• Beilstein号: 6467425
• MDL号: MFCD00038424

产品性质

• 纯度: ≥99% (HPLC)
• 外观: white powder
• 溶解度: H2O: soluble50 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).