Amyloid β-Protein Fragment 10-20_分子结构_CAS_152286-31-2)

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Amyloid β-Protein Fragment 10-20
产品号	A6825	公司名称	Sigma Aldrich
CAS号	152286-31-2	公司网站	http://www.sigmaaldrich.com
分子式	C71H99N17O16	电话	1-800-521-8956
分子量	1446.65006	传真
纯度		电子邮件
保存		Chembase数据库ID: 132169

产品价格信息

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产品别名

标题

Amyloid β-Protein Fragment 10-20

IUPAC标准名

(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]butanoic acid

IUPAC传统名

(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-carboxy-2-phenylethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]butanoic acid

产品登记号

CAS号	152286-31-2
MDL号	MFCD00467025

产品性质

主要成分	Protein content, ≥70%
相关基因信息	human ... APP(351)
外观	lyophilized powder
溶解度	0.1% TFA: soluble1 mg/mL
个人保护装置	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度	-20°C
德国WGK号	3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Tyr-Glu-Val-His-His-GlnLys-Leu-Val-Phe-Phe
Biochem/physiol Actions
Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) responsible for binding to microglial cells. This fragment is also a substrate for matrix metalloproteinase-2 (MMP-2 or gelatinase A).