1,2-Dioctanoyl-sn-glycerol

• 产品号: D5156
• CAS号: 60514-48-9
• 分子式: C19H36O5
• 分子量: 344.48614
• 纯 度: ≥96% (TLC)

产品别名

• 标题: 1,2-Dioctanoyl-sn-glycerol
• IUPAC标准名: (2S)-1-hydroxy-3-(octanoyloxy)propan-2-yl octanoate
• IUPAC传统名: (2S)-1-hydroxy-3-(octanoyloxy)propan-2-yl octanoate
• 别名: 1,2-Dicapryloyl-sn-glycerol; D-α,β-Dicaprylin; (S)-Glycerol 1,2-dioctanoate; DOG

产品登记号

• PubChem SID: 24893929
• CAS号: 60514-48-9
• Beilstein号: 1714754
• MDL号: MFCD00036835

产品性质

• 纯度: ≥96% (TLC)
• 运输包装: dry ice
• 外观: yellow oil
• 溶解度: DMSO: soluble
• 个人保护装置: Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• RTECS编号: RH0764500
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Caution
Some isomerization to the 1,3-isomer may occur in storage or in solution.
Other Notes
Synthetic 1,2-diglyceride of short chain fatty acid.
Biochem/physiol Actions
Cell-permeable, diacylglycerol (DAG) analog, and activator of protein kinase C (PKC). Shown to possess a lower affinity for the α isoform of PKC than for the other isoforms. Mimics the action of tumor-promoting phorbol esters, such as phorbol 12-myristate 13-acetate (PMA). Inhibits slow (L-type) Ca2+ current in rat heart cells independently of PKC activation and also inhibits the cGMP-gated channel in rod outer segments by a phosphorylation-independent mechanism.