3-Bromo-7-nitroindazole

• 产品号: B2050
• CAS号: 74209-34-0
• 分子式: C7H4BrN3O2
• 分子量: 242.02956
• 纯 度: ≥98% (TLC)

产品别名

• 标题: 3-Bromo-7-nitroindazole
• IUPAC标准名: 3-bromo-7-nitro-1H-indazole
• IUPAC传统名: 3-bromo-7-nitroindazole

产品登记号

• MDL号: MFCD00159910
• CAS号: 74209-34-0
• PubChem SID: 24278258

产品性质

• 纯度: ≥98% (TLC)
• 外观: light yellow powder
• 溶解度: ethanol: soluble25 mg/mL
• 溶解度: DMSO: soluble
• GHS警示词: Danger
• GHS危险声明: H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P308 + P313
• 危险公开号: 60
• 安全公开号: 53-22-36/37/39-45
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
A potent inhibitor of all nitric oxide synthase isoforms. Shows substantial neuroprotective effects against hypoxic damage (such as stroke) and animal models of Parkinsons disease. Crystallographic studies show that inhibition of eNOS is due to an induced cascade of conformation changes that ultimately dissociates the tetrahydrobiopterin cofactor from the enzyme.1