S-(-)-Carbidopa

• 产品号: C126
• CAS号: 28860-95-9
• 分子式: C10H14N2O4
• 分子量: 226.22916

产品别名

• 标题: S-(-)-Carbidopa
• IUPAC标准名: 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
• IUPAC传统名: carbidopa
• 别名: S-(-)-α-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid

产品登记号

• CAS号: 28860-95-9
• PubChem SID: 24277889
• MDL号: MFCD00069231
• EC号: 249-271-9

产品性质

• 相关基因信息: human ... DDC(1644)
• 紫外吸收波长: εmax/282.5 nm, methanol 2950
• 外观: white solid
• 比旋光度: [α]26/D -13.82°, c = 0.3 in methanol(lit.)
• RTECS编号: MW5298000
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Caution
Light sensitive
Biochem/physiol Actions
Peripheral inhibitor of L-aromatic amino acid decarboxylase. When co-administered with L-DOPA, it prevents extra-CNS conversion to dopamine, thereby increasing CNS concentrations of effective compounds. Selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells by increasing H2O2 in these cell lines, which are sensitive to reactive oxygen species.1