[D-Lys6]-LH-RH

• 产品号: L5022
• CAS号: 52671-12-2
• 分子式: C59H84N18O13
• 分子量: 1253.41106
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: [D-Lys6]-LH-RH
• IUPAC标准名: 6-amino-N-{1-[(5-carbamimidamido-1-{2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl}-1-oxopentan-2-yl)carbamoyl]-3-methylbutyl}-2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]hexanamide
• IUPAC传统名: 6-amino-N-[1-({5-carbamimidamido-1-[2-(carbamoylmethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl}carbamoyl)-3-methylbutyl]-2-[2-(3-hydroxy-2-{2-[3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]hexanamide

产品登记号

• MDL号: MFCD00133504
• CAS号: 52671-12-2
• PubChem SID: 24896386

产品性质

• 纯度: ≥95% (HPLC)
• 相关基因信息: human ... GNRH1(2796)
• 外观: powder
• GHS警示词: Danger
• GHS危险声明: H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P201-P308 + P313
• 危险公开号: 60
• 安全公开号: 53-22-36/37/39-45
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
pGlu-His-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
LH-RH agonist. It has been conjugated to cytotoxic compounds such as methotrexate (MTX), doxorubicin (DOX), and glutaryl-2-(hydroxymethyl)anthraquinone (G-HMAQ), and together with other conjugated LH-RH analogs comprise a class of targeted chemotherapeutic agents for cancers expressing receptors for LH-RH.