Bivalirudin

• 产品号: Bivalirudin
• CAS号: 128270-60-0
• 分子式: C98H138N24O33
• 分子量: 2180.28532

产品别名

• 标题: Bivalirudin
• IUPAC标准名: (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-(2-{2-[2-(2-{[(2S)-1-[(2S)-2-{[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)acetamido]acetamido}acetamido)-3-carbamoylpropanamido]acetamido}-3-carboxypropanamido]-3-phenylpropanamido]-4-carboxybutanamido]-4-{[(2S,3S)-1-[(2S)-2-{[(1S)-3-carboxy-1-{[(1S)-3-carboxy-1-{[(1S)-1-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}propyl]carbamoyl}propyl]carbamoyl}pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl]carbamoyl}butanoic acid
• IUPAC传统名: bivalirudin
• 商标名: Angiomax
• 别名: d-Phenylalanyl-l-prolyl-l-arginyl; -l-prolylglycylglycylglycylglycyl-l-asparaginylglycyl; -l-alpha-aspartyl-l-phenylalanyl; -l-alpha-glutamyl-l-alpha-glutamyl-l-isoleucyl; -l-prolyl-l-alpha-glutamyl-l-alpha-glutamyl; -l-tyrosyl-l-leucine

产品登记号

• 美国药典/FDA物质标识码: TN9BEX005G
• CHEBI ID: 59173
• PubChem CID: 16129704
• DrugBank ID: DB00006
• CHEMBL: 1201455
• CAS号: 128270-60-0
• 维基百科标题: Bivalirudin
• ATC码: B01AE06
• Chemspider ID: 10482069

产品性质

• 给药途径: Intravenous injection/infusion only
• 生物利用度: N/A (IV application only)
• 半衰期: ~25 minutes in patients with normal renal function
• 法定药品分级: Rx-only. Not a controlled substance.
• 代谢: Angiomax is cleared from plasma by a combination of renal mechanisms and proteolytic cleavage
• 妊娠期药物分类: B (US)