Goserelin

• 产品号: Goserelin
• CAS号: 65807-02-5
• 分子式: C59H84N18O14
• 分子量: 1269.41046

产品别名

• 标题: Goserelin
• IUPAC标准名: (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(tert-butoxy)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-[(diaminomethylidene)amino]pentanoyl]-N-(carbamoylamino)pyrrolidine-2-carboxamide
• IUPAC传统名: (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(tert-butoxy)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-[(diaminomethylidene)amino]pentanoyl]-N-(carbamoylamino)pyrrolidine-2-carboxamide
• 商标名: Zoladex
• 别名: D-Ser(But)^6Azgly^10LHRH

产品登记号

• ATC码: L02AE03
• Medline Plus: a601002
• PubChem CID: 5311128
• 美国药典/FDA物质标识码: 0F65R8P09N
• CAS号: 65807-02-5
• DrugBank ID: DB00014
• CHEMBL: 1201247
• 维基百科标题: Goserelin
• Chemspider ID: 4470656
• KEGG ID: D04405

产品性质

• 给药途径: implant
• 排泄: renal
• 半衰期: 4-5 hours
• 法定药品分级: Rx-only
• 妊娠期药物分类: D (3.6mg) / X (10.8mg) (USA)
• 蛋白结合率: 27.3%