Amphotericin B

• 产品号: Amphotericin_B
• CAS号: 1397-89-3
• 分子式: C47H73NO17
• 分子量: 924.07902

产品别名

• 标题: Amphotericin B
• IUPAC标准名: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
• IUPAC传统名: amphotericin B
• 商标名: Fungizone

产品登记号

• PubChem CID: 14956
• DrugBank ID: DB00681
• CHEMBL: 267345
• CAS号: 1397-89-3
• CHEBI ID: 2682
• Chemspider ID: 10237579
• 维基百科标题: Amphotericin_B
• ATC码: A01AB04
• ATC码: A07AA07
• ATC码: G01AA03
• ATC码: J02AA01
• KEGG ID: D00203

产品性质

• 给药途径: slow i.v.-infusion only
• 生物利用度: 100% (IV)
• 排泄: 40% found in urine after single cumulated over several days ; biliar excretion also important
• 半衰期: initial phase : 24 hours, ; second phase : approx. 15 days
• 法定药品分级: Rx-only, hospitalization recommended.
• 代谢: renal
• 妊娠期药物分类: B (US)