Rifabutin

• 产品号: Rifabutin
• CAS号: 72559-06-9
• 分子式: C46H62N4O11
• 分子量: 847.00468

产品别名

• 标题: Rifabutin
• IUPAC标准名: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
• IUPAC传统名: (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^4,^7.0^5,^3^1.0^2^6,^3^0]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
• 商标名: Mycobutin

产品登记号

• 维基百科标题: Rifabutin
• CHEBI ID: 45367
• CAS号: 72559-06-9
• 美国药典/FDA物质标识码: 1W306TDA6S
• Medline Plus: a693009
• Chemspider ID: 10482168
• DrugBank ID: DB00615
• CHEMBL: 444633
• KEGG ID: D00424
• PubChem CID: 6323490
• ATC码: J04AB04

产品性质

• 给药途径: Oral
• 生物利用度: 85%
• 排泄: Renal and fecal
• 半衰期: 28 to 62 hours (mean)
• 法定药品分级: POM (UK), ?-only (U.S.)
• 代谢: Hepatic
• 妊娠期药物分类: C (Australia), B (United States)
• 蛋白结合率: 85%