Vitamin B12

• 产品号: Vitamin_B12
• CAS号: 68-19-9
• 分子式: C63H88CoN14O14P
• 分子量: 1355.365181

产品别名

• 标题: Vitamin B12
• IUPAC标准名: cyano[(1R,2R,3R,4R,8S,13S,14S,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl)-4-{2-[(2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl phosphonato]oxy}propyl)carbamoyl]ethyl}-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^2,^5.1^7,^1^0.1^1^2,^1^5]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium
• IUPAC传统名: cyano[(1R,2R,3R,4R,8S,13S,14S,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl)-4-{2-[(2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl phosphonato]oxy}propyl)carbamoyl]ethyl}-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^2,^5.1^7,^1^0.1^1^2,^1^5]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium

产品登记号

• KEGG ID: D00166
• CHEMBL: 1697777
• PubChem CID: 5479203
• CAS号: 68-19-9
• Chemspider ID: 10469504
• 维基百科标题: Vitamin_B12
• ATC码: B03BA01
• DrugBank ID: DB00115

产品性质

• 给药途径: oral, IV, IM
• 生物利用度: readily absorbed in distal half of the ileum
• 排泄: renal
• 半衰期: Approximately 6 days; (400 days in the liver)
• 法定药品分级: POM (UK)
• 法定药品分级: OTC (US)
• 代谢: hepatic
• 蛋白结合率: Very high to specific transcobalamins plasma proteins; Binding of hydroxocobalamin is slightly higher than cyanocobalamin.