Domperidone

• 产品号: Domperidone
• CAS号: 57808-66-9
• 分子式: C22H24ClN5O2
• 分子量: 425.91126

产品别名

• 标题: Domperidone
• IUPAC标准名: 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
• IUPAC传统名: motilium
• 商标名: Motilium

产品登记号

• 美国药典/FDA物质标识码: 5587267Z69
• IUPHAR配体索引: 965
• CAS号: 57808-66-9
• CHEBI ID: 31515
• 维基百科标题: Domperidone
• DrugBank ID: DB01184
• PubChem CID: 3151
• Chemspider ID: 3039
• ATC码: QP51AX24
• ATC码: A03FA03
• KEGG ID: D01745
• CHEMBL: 219916

产品性质

• 给药途径: Oral, intravenous, rectal
• 生物利用度: High
• 排泄: Breast milk, renal
• 半衰期: 7 hours
• 法定药品分级: Not approved for use or sale: US; prescription medicine (POM): India, Australia, Canada, Israel; Over the Counter (OTC): UK (Pharmacy only), Belgium, Egypt, Ireland, Italy, Japan, Netherlands, South Africa, Switzerland, China, Russia, Slovakia, Thailand, Malta, South Korea, and Romania
• 代谢: Hepatic and intestinal (first-pass)
• 妊娠期药物分类: Not classified (US)
• 蛋白结合率: 91–93%