给药途径
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oral, rectal, intramuscular, intravenous (renal- and gallstones), topical
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排泄
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biliary, only 1% in urine
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半衰期
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1.2-2 hr (35% of the drug enters enterohepatic recirculation)
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法定药品分级
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Rx-only most preparations/countries, limited OTC in some countries, manufacture and veterinary use is banned in India, Nepal and Pakistan due to imminent extinction of local vultures
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法定药品分级
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P (UK)
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代谢
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hepatic, no active metabolites exist
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妊娠期药物分类
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C (1st. and 2nd. trimenon), D (third trimenon)
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妊娠期药物分类
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C (Australia)
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蛋白结合率
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more than 99%
|