Chlorpromazine

• 产品号: Chlorpromazine
• CAS号: 50-53-3
• 分子式: C17H19ClN2S
• 分子量: 318.86416

产品别名

• 标题: Chlorpromazine
• IUPAC标准名: [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine
• IUPAC传统名: chlorpromazine

产品登记号

• CHEBI ID: 3647
• CAS号: 50-53-3
• Medline Plus: a682040
• ATC码: N05AA01
• DrugBank ID: DB00477
• PubChem CID: 2726
• 美国药典/FDA物质标识码: U42B7VYA4P
• CHEMBL: 71
• Chemspider ID: 2625
• KEGG ID: D00270
• IUPHAR配体索引: 83
• 维基百科标题: Chlorpromazine

产品性质

• 给药途径: Oral, rectal (suppository), IM, IV infusion
• 生物利用度: Oral, 30 to 50% (interindividual variations 10–70%)
• 排泄: Biliary and renal, as metabolites (only traces of unchanged drug)
• 半衰期: 16 to 30 hours. In long term treatment, CPZ induces its own metabolism
• 法定药品分级: Rx-only
• 代谢: Hepatic, mostly CYP2D6-mediated
• 妊娠期药物分类: C—only when benefit for the mother exceeds risk to unborn child