Betazole

• 产品号: DB00272
• CAS号: 105-20-4
• 分子式: C5H9N3
• 分子量: 111.14506

产品别名

• 标题: Betazole
• IUPAC标准名: 2-(1H-pyrazol-5-yl)ethan-1-amine
• IUPAC传统名: ametazole
• 商标名: Histalog
• 别名: Ametazole; Betazolo [DCIT]; Betazolum [INN-Latin]; Betazol [INN-Spanish]

产品登记号

• PubChem SID: 46506808
• CAS号: 105-20-4
• PubChem CID: 7741

产品性质

• 疏水性(logP): 0.1

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: A histamine H2 agonist used clinically to test gastric secretory function. [PubChem]
• Indication: For use clinically to test gastric secretory function.
• Pharmacology: Betazole is a histamine H2 agonist used in a test for measuring maximal production of gastric acidity or anacidity. This measurement can be used to diagnose diseases such as Zollinger-Ellison syndrome, whereby the volume of gastric and basal secretions is measured following betazole administration (greater than 60% of the maximal acid secretion following betazole stimulation). In another test, gastritis can be diagnosed given late absence of gastric acid which is unresponsive to betazole stimulation. Betazole can be used as a gastric secretory stimulant instead of histamine with the advantage of not provoking side effects and thus not requiring the use of antihistaminic compounds.
• Affected Organisms: Humans and other mammals
• Absorption: Rapid and complete.
• Protein Binding: > 99%
• External Links: Wikipedia