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L-Aspartic Acid

产品号 DB00128 公司名称 DrugBank
CAS号 56-84-8 公司网站 http://www.ualberta.ca/
分子式 C4H7NO4 电 话 (780) 492-3111
分子量 133.10268 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 14

产品价格信息

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产品别名

标题
L-Aspartic Acid
IUPAC标准名
(2S)-2-aminobutanedioic acid
IUPAC传统名
L-aspartic acid
商标名
Aspatofort
别名
(+)-Aspartic acid
(2S)-Aspartic acid
(L)-Aspartic acid
(S)-Aminobutanedioic acid
(S)-Aspartic acid
Acide aspartique [INN-French]
Acido aspartico [INN-Spanish]
Acidum asparticum
Aminosuccinic acid
Asparagic acid
Asparaginic acid
Asparaginsaeure [German]
Aspartate
Aspartic acid
H-Asp-OH
L-(+)-Aspartic acid
L-2-Aminobutanedioic acid
L-Aminosuccinic acid
L-Asparagic acid
L-Asparaginic acid
L-Asparaginsaeure
L-Asparaginsyra
L-Aspartinsaeure

产品登记号

CAS号 56-84-8
PubChem CID 5960
PubChem SID 46507997

产品性质

疏水性(logP) -3.7
溶解度 4.5 g/l

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; nutraceutical
Description One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter. [PubChem]
Indication There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.
Pharmacology L-aspartate is considered a non-essential amino acid, meaning that, under normal physiological conditions, sufficient amounts of the amino acid are synthesized in the body to meet the body's requirements. L-aspartate is formed by the transamination of the Krebs cycle intermediate oxaloacetate. The amino acid serves as a precursor for synthesis of proteins, oligopeptides, purines, pyrimidines, nucleic acids and L-arginine. L-aspartate is a glycogenic amino acid, and it can also promote energy production via its metabolism in the Krebs cycle. These latter activities were the rationale for the claim that supplemental aspartate has an anti-fatigue effect on skeletal muscle, a claim that was never confirmed.
Toxicity Mild gastrointestinal side effects including diarrhea. LD50 (rat) > 5,000 mg/kg.
Affected Organisms
Humans and other mammals
Absorption Absorbed from the small intestine by an active transport process
External Links
Wikipedia
PDRhealth

参考文献