| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
An antibiotic derived from penicillin similar to carbenicillin in action. |
| Indication |
For the treatment of bacterial infections. |
| Pharmacology |
Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. Ticarcillin is, however, susceptible to degradation by ?-lactamases, and therefore, the spectrum of activity does not normally include organisms which produce these enzymes. |
| Toxicity |
As with other penicillins, neurotoxic reactions may arise when very high doses of ticarcillin are administered, especially in patients with impaired renal function. |
| Affected Organisms |
| • |
Enteric bacteria and other eubacteria |
|
| Half Life |
1.1 hours |
| Protein Binding |
45% |
| External Links |
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