| Item |
Information |
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Drug Groups
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approved |
|
Description
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A sulfanilamide that is used as an antibacterial agent. [PubChem] |
| Indication |
A sulfanilamide that is used as an antibacterial agent. It can be used to treat bronchitis, prostatitis and urinary tract infections. |
| Pharmacology |
Sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis in bacteria. |
| Toxicity |
Sulfamerazine may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns. |
| Absorption |
Rapidly absorbed following oral administration. |
| External Links |
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