Biotin-Val-Ala-Asp(OMe)-Fluoromethylketone

• 产品号: 03FK014
• 分子式: C30H49FN6O8S
• 分子量: 672.8088632

产品别名

• 标题: Biotin-Val-Ala-Asp(OMe)-Fluoromethylketone
• IUPAC标准名: methyl (3S)-3-[(2S)-2-[(2S)-2-(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanamido)-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
• IUPAC传统名: methyl (3S)-3-[(2S)-2-[(2S)-2-(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydrothieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanamido)-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate
• 别名: Biotin-VAD(OMe)-FMK; Biotin-Val-Ala-Asp(OMe)-FMK

产品详细信息

详细说明 (English)

An inhibitor/probe for General Caspases. Biotinylated derivative of Z-VAD(OMe)-FMK that may be used to identify active caspases in cell lysates. There is a linker molecule (epsilon-AMINO-N-CAPROIC ACID) between biotin and the peptide.

参考文献

• Bombeck, C.A. et al., J. Biol. Chem., 274(24):17325 (1999).
• Li, S. et al. 1999. J. Biol. Chem. 274, 17325.
• Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.