Ac-Ile-Glu-Thr-Asp-7-Amino-4-Methylcoumarin

• 产品号: 03AMC140
• 分子式: C31H41N5O12
• 分子量: 675.68354

产品别名

• 标题: Ac-Ile-Glu-Thr-Asp-7-Amino-4-Methylcoumarin
• IUPAC标准名: (4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid
• IUPAC传统名: (4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid
• 别名: Ac-Ile-Glu-Thr-Asp-AMC; Ac-IETD-AMC

产品详细信息

详细说明 (English)

A fluorogenic substrate for Caspase-8 and Granzyme B.

参考文献

• Thornberry, H.A. et al., Science, 281:1312 (1998).
• Talanian, R.V. et al., J. Biol. Chem., 272:9677 (1997).