Z-Asp-Glu-Val-Asp-7-Amino-4-trifluoromethylcoumarin

• 产品号: 03AFC138Z
• 分子式: C36H38F3N5O14
• 分子量: 821.7072296

产品别名

• 标题: Z-Asp-Glu-Val-Asp-7-Amino-4-trifluoromethylcoumarin
• IUPAC标准名: (4S)-4-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-2-carboxy-1-{[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}butanoic acid
• IUPAC传统名: (4S)-4-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-2-carboxy-1-{[2-oxo-4-(trifluoromethyl)chromen-7-yl]carbamoyl}ethyl]carbamoyl}-2-methylpropyl]carbamoyl}butanoic acid
• 别名: Z-Asp-Glu-Val-Asp-AFC; Z-DEVD-AFC

产品详细信息

详细说明 (English)

A fluorogenic substrate for Caspase-3 (CPP32, YAMA). Also acts as a substrate for granzyme B-processed ICE-LAP3. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10.
Excitation max.: ~400 nm, Emission max.: ~505 nm

参考文献

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