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Delta1-dihydrotestosterone

产品号 DB01481 公司名称 DrugBank
CAS号 65-06-5 公司网站 http://www.ualberta.ca/
分子式 C19H28O2 电 话 (780) 492-3111
分子量 288.42442 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 1278

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产品别名

标题
Delta1-dihydrotestosterone
IUPAC标准名
(1S,2R,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-3-en-5-one
IUPAC传统名
delta1-dihydrotestosterone
别名
17beta-hydroxy-5alpha-androst-1-en-3-one
1-testosterone
1-Testo
1-T

产品登记号

PubChem CID 236666
PubChem SID 46507716
CAS号 65-06-5

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups illicit; experimental
Description Delta1-dihydrotestosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. [Wikipedia]
Pharmacology Delta1-dihydrotestosterone binds to the androgen receptor, a nuclear receptor which binds the androgenic hormones testosterone and dihydrotestosterone. Once bound, the receptor/ligand complex localizes to the nucleus and acts as a DNA binding transcription factor, regulating gene expression. In animals, Delta1-dihydrotestosterone stimulates the growth of the prostate as well as the seminal vesicles.
Affected Organisms
Humans and other mammals
References
Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schanzer W, Thevis M, Vollmer G, Zierau O, Diel P: 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties. Toxicol Lett. 2006 Aug 20;165(2):149-55. Epub 2006 Apr 18. [Pubmed]

参考文献

  • Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schanzer W, Thevis M, Vollmer G, Zierau O, Diel P: 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties. Toxicol Lett. 2006 Aug 20;165(2):149-55. Epub 2006 Apr 18. Pubmed