| Item |
Information |
|
Drug Groups
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approved |
|
Description
|
A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. [PubChem] |
| Indication |
For the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. |
| Pharmacology |
Phenazopyridine is a local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. |
| Toxicity |
Methemoglobinemia generally follows a massive, acute overdose. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
Likely hepatic but also in other tissues. One of the metabolites is acetaminophen. |
| Half Life |
7.35 hours |
| Elimination |
40% hepatic |
| External Links |
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