Alizapride

• 产品号: DB01425
• CAS号: 59338-93-1
• 分子式: C16H21N5O2
• 分子量: 315.37024

产品别名

• 标题: Alizapride
• IUPAC标准名: 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-1,2,3-benzotriazole-5-carboxamide
• IUPAC传统名: alizapride
• 商标名: Liticum; Limican
• 别名: Alizaprida [inn-spanish]; Alizapridum [inn-latin]

产品登记号

• PubChem SID: 46505555
• CAS号: 59338-93-1
• PubChem CID: 43008

产品性质

• 疏水性(logP): 1.79 [MANNHOLD,R ET AL. (1990)]

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
• Indication: Alizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
• Pharmacology: Alizapride is a dopamine antagonist.
• Half Life: 3 hours
• Elimination: renal
• References: Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. [Pubmed]
• External Links: Wikipedia

参考文献

• Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Pubmed