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Salicylate-sodium

产品号 DB01398 公司名称 DrugBank
CAS号 公司网站 http://www.ualberta.ca/
分子式 C7H5NaO3 电 话 (780) 492-3111
分子量 160.10257 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 1209

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标题
Salicylate-sodium
IUPAC标准名
sodium 2-hydroxybenzoate
IUPAC传统名
potassium o-hydroxybenzoate

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Item Information
Drug Groups approved
Description Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure.

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID) and induces apoptosis in cancer cells. It is also potential replacement for aspirin for people sensitive to it.
Indication It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID)
Pharmacology Non-steroidal anti-inflammatory drugs such as Salicylate-sodium work by inhibiting the enzyme cyclooxygenase (COX), which converts arachidonic acid to prostaglandin H2 (PGH2). PGH2, in turn, is converted by other enzymes to several other prostaglandins (which are mediators of pain, inflammation, and fever)
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