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Vitamin C

产品号 DB00126 公司名称 DrugBank
CAS号 50-81-7 公司网站 http://www.ualberta.ca/
分子式 C6H8O6 电 话 (780) 492-3111
分子量 176.12412 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 12

产品价格信息

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产品别名

标题
Vitamin C
IUPAC标准名
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
IUPAC传统名
vitamin C
商标名
Adenex
Allercorb
Antiscorbic Vitamin
Antiscorbutic Vitamin
Arco-Cee
Ascoltin
Ascor-B.I.D.
Ascorb
Ascorbajen
Ascorbicab
Ascorbicap
Ascorbicin
Ascorbin
Ascorbutina
Ascorin
Ascorteal
Ascorvit
C-Level
C-Long
C-Quin
C-Span
C-Vimin
Cantan
Cantaxin
Cetane-Caps Tc
Cevital
Cevalin
Hicee
Citriscorb
Colascor
Cebid
Cevitamin
Cebicure
Ce Lent
Cegiolan
Cevitex
Concemin
Duoscorb
Hybrin
Cescorbat
Cetamid
Cenetone
Celaskon
Cevatine
Cereon
Cevimin
Cee-Caps Td
Cergona
Cenolate
Cevitamic Acid
Cetebe
IDO-C
Cebione
Cewin
Cetane-Caps Td
Cetane
Davitamon C
Cee-Vite
Cemagyl
Cevi-Bid
Cipca
Cecon
Cemill
Cevex
Kyselina Askorbova
Ceglion
Catavin C
Cetemican
Ciamin
Cevitan
Cebion
Celin
Planavit C
Testascorbic
Ribena
Laroscorbine
Liqui-Cee
Vicelat
Roscorbic
Viforcit
Natrascorb
Vicin
Scorbacid
Redoxon
Sodascorbate
Proscorbin
Meri-C
Vicomin C
Lemascorb
Scorbu-C
Secorbate
Vitacin
Vitamisin
Vitascorbol
Vitacimin
Vitace
Xitix
Vitacee
Viscorin
别名
Ascorbate
L-Ascorbate
L-Xyloascorbic Acid
Ascorbic Acid
AA
L-Ascorbic Acid
L-Lyxoascorbic Acid

产品登记号

CAS号 50-81-7

产品性质

疏水性(logP) -0.5
溶解度 40 g/L

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; nutraceutical
Description A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. [PubChem]
Indication Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Pharmacology Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency.
Affected Organisms
Humans and other mammals
Biotransformation Hepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolized to inactive compounds including ascorbic acid-2-sulfate and oxalic acid.
Absorption 70% to 90%
Half Life 16 days (3.4 hours in people who have excess levels of vitamin C)
Protein Binding 25%
References
Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M: Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35. [Pubmed]
Meister A: Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem. 1994 Apr 1;269(13):9397-400. [Pubmed]
Englard S, Seifter S: The biochemical functions of ascorbic acid. Annu Rev Nutr. 1986;6:365-406. [Pubmed]
Banhegyi G, Mandl J: The hepatic glycogenoreticular system. Pathol Oncol Res. 2001;7(2):107-10. [Pubmed]
Proctor P: Similar functions of uric acid and ascorbate in man? Nature. 1970 Nov 28;228(5274):868. [Pubmed]
External Links
Wikipedia
RxList
PDRhealth
Drugs.com

参考文献

  • Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M: Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35. Pubmed
  • Meister A: Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem. 1994 Apr 1;269(13):9397-400. Pubmed
  • Englard S, Seifter S: The biochemical functions of ascorbic acid. Annu Rev Nutr. 1986;6:365-406. Pubmed
  • Banhegyi G, Mandl J: The hepatic glycogenoreticular system. Pathol Oncol Res. 2001;7(2):107-10. Pubmed
  • Proctor P: Similar functions of uric acid and ascorbate in man? Nature. 1970 Nov 28;228(5274):868. Pubmed