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Information |
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Drug Groups
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approved |
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Description
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One of the angiotensin-converting enzyme inhibitors (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. [PubChem] |
| Indication |
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. |
| Pharmacology |
Cilazapril inhibits the production angiotensin II. By doing so, it decreases sodium and water reabsorption (via aldosterone) and it decreases vasoconstriction. The combined effect of this is a decrease in vascular resistance, and therefore, blood pressure. |
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