Vecuronium

• 产品号: DB01339
• CAS号: 50700-72-6
• 分子式: C34H57N2O4+
• 分子量: 557.82738

产品别名

• 标题: Vecuronium
• IUPAC标准名: 1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-5,14-bis(acetyloxy)-2,15-dimethyl-4-(piperidin-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-methylpiperidin-1-ium
• IUPAC传统名: vecuronium

产品登记号

• PubChem SID: 46507656
• PubChem CID: 39765
• CAS号: 50700-72-6

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents. [PubChem]
• Indication: Vecuronium is a muscle relaxing agent and is used as an ajunct in general anesthesia.
• Pharmacology: Vecuronium operates by competing for the cholinoceptors at the motor end plate thereby exerting its muscle-relaxing properties which are used adjunctively to general anesthesia.
• Biotransformation: 100%
• Half Life: 51–80 minutes
• Elimination: Fecal (40-75%) and renal (30% as unchanged drug and metabolites)
• External Links: Wikipedia; Drugs.com