| Item |
Information |
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Drug Groups
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approved |
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Description
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A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. [PubChem] |
| Indication |
For the treatment of infections due to susceptible strains of microorganisms. |
| Pharmacology |
Ceftizoxime is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. |
| Affected Organisms |
| • |
Enteric bacteria and other eubacteria |
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| Biotransformation |
Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours. |
| Protein Binding |
30% protein bound |
| Elimination |
Ceftizoxime is not metabolized, and is excreted virtually unchanged by the kidneys in 24 hours. |
| External Links |
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