Josamycin

• 产品号: DB01321
• CAS号: 16846-24-5
• 分子式: C42H69NO15
• 分子量: 827.99496

产品别名

• 标题: Josamycin
• IUPAC标准名: (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate
• IUPAC传统名: josamycin
• 商标名: Turimycin A5; Josacine; Kitasamycin A3
• 别名: Josamicina [inn-spanish]; Leucomycin V, 3-acetate 4B-(3-methylbutanoate); Leucomycin A3; JM; Antibiotic yl-704 A3; Josamycine [inn-french]; Josamycinum [inn-latin]; Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate); Leucomycin V, 3-acetate 4(sup beta)-(3-methylbutanoate)

产品登记号

• PubChem CID: 5282165
• PubChem SID: 46505431
• CAS号: 16846-24-5

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. [PubChem]
• Indication: For the treatment of bacterial infections.
• Pharmacology: Josamycin is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
• Affected Organisms: Enteric bacteria and other eubacteria
• References: Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96. [Pubmed]
• External Links: Wikipedia

参考文献

• Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96. Pubmed