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Oxtriphylline

产品号 DB01303 公司名称 DrugBank
CAS号 4499-40-5 公司网站 http://www.ualberta.ca/
分子式 C12H21N5O3 电 话 (780) 492-3111
分子量 283.32684 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 1153

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产品别名

标题
Oxtriphylline
IUPAC标准名
(2-hydroxyethyl)trimethylazanium; 1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide
IUPAC传统名
1,3-dimethyl-2,6-dioxo-7H-purin-7-ide; choline
商标名
Theocolin
Choledyl
别名
Choline theophylline

产品登记号

PubChem CID 656652
PubChem SID 46507376
CAS号 4499-40-5

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Oxtriphylline is a cough medicine derived from xanthine and similar to theophylline, that acts as a bronchodilator to open up airways in the lung. It antagonizes adenosine receptors and promotes relaxation of airway smooth muscles. It is also thought to inhibit phosphodiesterases leading to higher levels of cAMP and increased bronchodilation.
Indication Used to treat the symptoms of asthma, bronchitis, and emphysema.
Pharmacology Oxtriphylline is a bronchodilator. Oxtriphylline works in several ways: it relaxes muscles in your lungs and chest to allow more air in, decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and increases the contractions of your diaphragm to draw more air into the lungs.
Toxicity Symptoms of toxicity include abdominal pain (continuing or severe), confusion or change in behavior, convulsions (seizures), dark or bloody vomit, diarrhea, dizziness or lightheadedness, fast and/or irregular heartbeat, nervousness or restlessness (continuing), and trembling (continuing).
Affected Organisms
Humans and other mammals
External Links
Wikipedia
Drugs.com

参考文献