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Practolol

产品号 DB01297 公司名称 DrugBank
CAS号 6673-35-4 公司网站 http://www.ualberta.ca/
分子式 C14H22N2O3 电 话 (780) 492-3111
分子量 266.33608 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 1149

产品价格信息

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产品别名

标题
Practolol
IUPAC标准名
N-{4-[(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl}acetamide
IUPAC传统名
@practolol
别名
Tocris-0831

产品登记号

CAS号 6673-35-4

产品性质

疏水性(logP) 0.79 [HANSCH,C ET AL. (1995)]

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. [PubChem]
Indication Used in the emergency treatment of cardiac arrhythmias.
Pharmacology Practolol is a beta-adrenergic receptor antagonist that has been used in the emergency treatment of cardiac arrhythmias. Beta blockers inhibit normal epinephrine-mediated sympathetic actions, but have minimal effect on resting subjects. That is, they reduce the effect of excitement/physical exertion on heart rate and force of contraction and dilation of blood vessels.
Toxicity Symptoms of overdose include abdominal irritation, central nervous system depression, coma, extremely slow heartbeat, heart failure, lethargy, low blood pressure, and wheezing.
External Links
Wikipedia

参考文献