Bevantolol

• 产品号: DB01295
• CAS号: 59170-23-9
• 分子式: C20H27NO4
• 分子量: 345.43268

产品别名

• 标题: Bevantolol
• IUPAC标准名: [2-(3,4-dimethoxyphenyl)ethyl][2-hydroxy-3-(3-methylphenoxy)propyl]amine
• IUPAC传统名: bevantololum
• 别名: 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [inn-latin]

产品登记号

• PubChem CID: 2372
• PubChem SID: 46506014
• CAS号: 59170-23-9

产品性质

• 疏水性(logP): 3.00 [HANSCH,C ET AL. (1995)]

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
• Indication: For the treatment of angina pectoris and hypertension.
• Pharmacology: Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.
• Affected Organisms: Humans and other mammals
• References: Vaughan Williams EM: Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60. [Pubmed]

参考文献

• Vaughan Williams EM: Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60. Pubmed