| Item |
Information |
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Drug Groups
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approved |
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Description
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Chloroxine is a synthetic antibacterial compound. Chloroxine is a compound used in some shampoos for the treatment of dandruff and seborrheic dermatitis of the scalp. |
| Indication |
Used in the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp. |
| Pharmacology |
Chloroxine has an antibacterial action, inhibiting the growth of gram-positive as well as some gram-negative organisms. Also, chloroxine has shown some antifungal activity against certain dermatophytes and yeasts. |
| Toxicity |
The toxicological properties of this material have not been investigated. |
| Affected Organisms |
| • |
Humans and other mammals |
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| References |
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Malaveille C, Brun G, Bartsch H: Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: studies on their mode of action. IARC Sci Publ. 1991;(115):261-6.
[Pubmed]
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| • |
Malaveille C, Brun G, Bartsch H: Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites. Mutat Res. 1994 May 1;307(1):141-7.
[Pubmed]
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| External Links |
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