| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan. [Wikipedia] |
| Indication |
For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
There is no detectable biotransformation or decomposition of gadodiamide. |
| Half Life |
Two-compartment model with mean distribution and elimination half-lives (reported as mean ± SD) of 3.7 ± 2.7 minutes and 77.8 ± 16 minutes, respectively. |
| Elimination |
Gadodiamide is eliminated primarily in the urine. |
| Distribution |
* 200 ± 61 mL/kg |
| Clearance |
* Renal cl=1.7 mL/min/kg
* Plasma cl=1.8 mL/min/kg |
| External Links |
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