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Oxyphenonium

产品号 DB00219 公司名称 DrugBank
CAS号 50-10-2 公司网站 http://www.ualberta.ca/
分子式 C21H34NO3+ 电 话 (780) 492-3111
分子量 348.49956 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 104

产品价格信息

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产品别名

标题
Oxyphenonium
IUPAC标准名
{2-[(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxy]ethyl}diethylmethylazanium
IUPAC传统名
spasmophen
商标名
Methacin
Methocidin
Antrenyl
Argicillin
别名
Methocidin [Dcf:Inn]
Oxiphenonum
Hydroxymethylgramicidin
Methocidinum [INN-Latin]
Methocidine [INN-French]
Metocidina [INN-Spanish]
Oxyphenonium Bromide
DCF

产品登记号

PubChem SID 46508840
PubChem CID 5749
CAS号 50-10-2

产品性质

疏水性(logP) 0.17

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]
Indication For the treatment of visceral spasms
Pharmacology Oxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Oxyphenonium inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.
Affected Organisms
Humans and other mammals
Protein Binding 93% bound to albumin

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