| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
A guanidinium antihypertensive agent that acts by blocking adrenergic transmission. |
| Indication |
For the treatment of hypertension. |
| Pharmacology |
Bethanidine is a guanidinium antihypertensive agent that acts by blocking adrenergic transmission. The precise mode of action is not clear. Although bethanidine may produce adverse effects, they are beneficial in severe hypertension and produce fewer side effects than guanethidine. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Absorption |
Absorbed rapidly in the gastrointestinal tract following oral administration. |
| Half Life |
9 hours (range 7 to 11 hours) |