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Cefadroxil

产品号 DB01140 公司名称 DrugBank
CAS号 66592-87-8 公司网站 http://www.ualberta.ca/
分子式 C16H17N3O5S 电 话 (780) 492-3111
分子量 363.38828 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 1011

产品价格信息

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产品别名

标题
Cefadroxil
IUPAC标准名
7-[2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
IUPAC传统名
cefadroxil
商标名
Cefa-Drops
Cefamox
Kefroxil
Ultracef
Baxan
Bidocef
Cephos
Duracef
Oracefal
Sedral
Sumacef
别名
CDX
Cefradroxil
Cefadroxil Monohydrate

产品登记号

CAS号 66592-87-8

产品性质

疏水性(logP) -0.4
溶解度 1110 mg/L

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Long-acting, broad-spectrum, water-soluble, cephalexin derivative. [PubChem]
Indication For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Pharmacology Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
Toxicity Nausea, vomiting, diarrhoea, allergic rashes may occur
Affected Organisms
Enteric bacteria and other eubacteria
Absorption Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
Half Life 1.5 hours
Protein Binding Binding rates of cefadroxil were 28.1% by U.F. method
Elimination Over 90% of the drug is excreted unchanged in the urine within 24 hours. It crosses the placenta and appears in breast milk.
External Links
Wikipedia
RxList
Drugs.com

参考文献