4-chloronaphthalen-1-ol

• ChemBase编号: 75375
• 分子式: C10H7ClO
• 平均质量: 178.61498
• 单一同位素质量: 178.01854252
• SMILES: Oc1c2ccccc2c(cc1)Cl
• Canonical SMILES: Clc1ccc(c2c1cccc2)O
• InChI: InChI=1S/C10H7ClO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H
• InChIKey: LVSPDZAGCBEQAV-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: 4-chloronaphthalen-1-ol
• IUPAC传统名: 4-chloro-1-naphthol
• 别名: 4-氯-1-萘酚; 4-氯-1-萘酚 溶液; 4-Chloro-1-hydroxynaphthalene; 4-Chloro-1-naphthol; 4-Chloro-1-naphthol; 4-Chloro-1-naphthol solution; 4-chloronaphthalen-1-ol

登记号

• CAS号: 604-44-4
• EC号: 210-068-5
• MDL号: MFCD00003974
• Beilstein号: 509750
• PubChem SID: 24892896; 162040293; 24855304; 24893113; 24893047
• PubChem CID: 11787

理论计算性质

• Acid pKa: 8.607161
• 质子受体: 1
• 质子供体: 1
• LogD (pH = 5.5): 3.2628648
• LogD (pH = 7.4): 3.2372231
• Log P: 3.263202
• 摩尔折射率: 49.2939 cm^3
• 极化性: 20.319906 Å^3
• 极化表面积: 20.23 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: methanol: soluble50 mg/mL, clear, colorless to very faintly yellow
• 外观: crystalline; tablet
• 熔点: 118-120 °C; 118-121 °C(lit.); 120 - 121°C; 120-121°C
• 闪点: 163.4 °F; 73 °C
• 疏水性(logP): 3.659
• 荧光: λex 310 nm; λem 375 nm in ethanol

安全信息

• 保存条件: 0°C; 2-8°C
• 保存注意事项: Irritant/Light Sensitive/Store under Argon
• 欧盟危险性物质标志: 有毒(Toxic) (T); 刺激性(Irritant) (Xi)
• 联合国危险货物编号: 2810
• 德国WGK号: 1; 3
• 联合国危险货物等级: 6.1
• 联合国危险货物包装类别(PG): 3
• 危险公开号: 20/21/22-39/23/24/25; 36/37/38; R:36/37/38
• 安全公开号: 26-36; 36/37; S:20-25-26-37/39
• GHS危险品标识: GHS07; GHS08
• GHS警示词: Danger; Warning
• GHS危险声明: H302-H312-H332-H370; H315-H319-H335
• GHS警示性声明: P260-P280-P307 + P311; P261-P305 + P351 + P338
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves; Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• RID/ADR: UN 2810 6.1/PG 3
• 保存温度: -20°C; 2-8°C

产品相关信息

• 纯度: ≥99.0%; ≥99.0% (HPLC); 95%; 95+%; 97%; 99%
• 级别: for analytical purposes
• 线性分子式: ClC10H6OH

详细说明

MP Biomedicals - 05215236

MP Biomedicals Rare Chemical collection

MP Biomedicals - 02152347

Stabilized Chromogen Chromogen solution for immunohistology procedures and peroxidase and pseudo-peroxidase reactions. Ready-to-use directly as the final step in developing the color indicator in the enzyme reaction. Precipitates as a readily detected marker for immunohistopathological staining. Stable up to 15 months.

MP Biomedicals - 02150629

Purity: 97%
Off-white to tan crystals.

Sigma Aldrich - C6788

Quantity
Contains 30 mg substrate per tablet.
Reconstitution
Dissolve 1 tablet in 10 ml of methanol. Add 2 ml of methanol stock solution to 10 ml of triethanolamine buffered saline, pH 7.5. Add 5 μl of fresh 30% hydrogen peroxide (Sigma Product No. H-1009) immediately prior to use.
Specificity
4-Chloro-1-Naphthol is a peroxidase substrate suitable for use in immunoblotting procedures. This substrate produces an insoluble end product that is blue in color and can be observed visually.

Sigma Aldrich - C8302

Other Notes
0.48 mM 4-chloro-1-naphthol, 50 mM Tris-HCl, 0.2 M NaCl and 17% methanol.
Substrates
Substrate for visualizing peroxidase conjugates in Western blotting.

Sigma Aldrich - C8890

包装
2.5, 5, 25, 100 g in glass bottle
Substrates
Chromogenic peroxidase substrate useful in enzyme-linked detection procedures.

Sigma Aldrich - 317403

Application
可用于过氧化物酶染色实验。1

Sigma Aldrich - 25328

Application
电泳试验：适用于印迹膜上的过氧化物酶检测
Other Notes
可用于过氧化物酶染色实验。在等电点聚焦和免疫印迹实验中转入硝化纤维膜后检测特定抗原1；在斑点免疫结合试验中用于检测和定量人 IgE22；可用于快速多色蛋白质印迹实验3

Sigma Aldrich - C57804

包装
25 g in glass bottle

参考文献

• Jarrell, K.F., et al., Molecular Microbiology , 20(3) : 657 (1996).