(2R,3S,4R,5R,8R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

• ChemBase编号: 73255
• 分子式: C38H72N2O12
• 平均质量: 748.98448
• 单一同位素质量: 748.50852575
• SMILES: [C@@H]1([C@@]([C@@H](OC(=O)[C@@H]([C@@H]([C@@H]([C@H](C(C[C@H](CN([C@H]1C)C)C)(C)O)O[C@@H]1O[C@@H](C[C@@H]([C@H]1O)N(C)C)C)C)OC1C[C@@]([C@H]([C@@H](O1)C)O)(C)OC)C)CC)(O)C)O
• Canonical SMILES: CC[C@@H]1OC(=O)[C@H](C)[C@H](OC2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)C(C[C@H](CN([C@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O
• InChI: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28?,29-,30+,31-,32+,33-,35+,36?,37-,38-/m1/s1
• InChIKey: MQTOSJVFKKJCRP-HODBGXSSSA-N

名称和登记号

名称

• IUPAC标准名: (2R,3S,4R,5R,8R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
• IUPAC传统名: (2R,3S,4R,5R,8R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
• 别名: Zithromax; Azithromycin

登记号

• CAS号: 83905-01-5
• PubChem SID: 162038175
• PubChem CID: 25235496

理论计算性质

• Acid pKa: 12.428324
• 质子受体: 13
• 质子供体: 5
• LogD (pH = 5.5): -4.14965
• LogD (pH = 7.4): -1.2309437
• Log P: 2.4447815
• 摩尔折射率: 194.1082 cm^3
• 极化性: 79.00683 Å^3
• 极化表面积: 180.08 Å^2
• 可自由旋转的化学键: 7
• 里宾斯基五规则: false

分子性质

安全信息

• 保存条件: -20°C

详细说明

Selleck Chemicals - S1835

Biological Activity: